<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    V31I, M50I, I72T, K111Q, T112V, T124A, T125A, I135V, K136T, V201I, T206S, Q221S, L234I S283G
>78_LH02| codons 1-288
FLDGIDKAQEEHEKYHSNWRAMASDFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKTILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVQVIHTDNGSN
FTSAAVKAACWWAGVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKISNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12Q, I13V, L19P, K20I, M36I, R41K, I64L, H69K, K70R, L89M  
>78_LH02| codons 1-99
PQITLWQRPVVQVKIGGQPIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILLEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39K, V60I, K122P, I135V, S162A, K173T, Q174E, D177E, I178V, T200A, Q207E, V245H, A272P, T286A, K287Q, E291A, V292T, I293V, P294T, S322T, G335D, R356K, M357R, G359S, A371V, S379G, T403M, A408V, E413D, E432D, V435I, L469I, D471E, L491S, K512S, L517I, S519N, Q524K, K527E, E529D, A534S, A554N, K558R  
>78_LH02| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DPDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEVVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIHLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAQALTATVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKRRSA
HTNDVKQLTEVVQKIATEGIVIWGKTPKFKLPIQKETWEAWWMEYWQVTWIPDWEFVNTP
PLVKLWYQLEKDPIIGAETFYVDGAANRETKLGKAGYVTDRGRQKVVSITETTNQKTELQ
AIHLALQDSGSEVNIVTDSQYALGIIQAQPDSSESEIVNQIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSNGIRRVL

References
Author Title Citation
Manak, M Pilot studies for development of an HIV subtype panel for surveillance of global diversity. ARHR, 2012