<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I13V, K14R, I15V, G17D, L19I, K20M, N37S, L63P, H69K, L89M, I93L  
>08_LH08| codons 1-99
PQITLWQRPLVSVRVGDQIMEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      A98G V35T, T39E, S48T, V118I, K122E, D123S, I135R, T165I, K173A, D177E, T200A, E204Q, Q207E, R211K, F214L, K223R, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, T369A, T377M, K390R, A400I, E404D, K431T, V435A, A437V, R461K, V466I, V467I, S468F, D471E, T477A, H483Q, L491S, L517I, S519N, K527S, K530R, V531I, A534S, A554S E79EG
>08_LH08| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRGLNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRAQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEQLREHLLKWGLTTPDKKHQREPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA
HTNDVKQLAEAVQKIAMESIVIWGKTPKFRLPIQKETWEIWWTDYWQATWIPEWEFVNTP
PLVKLWYQLETEPIAGVETFYVDGAANRETKLGKAGYVTDKGRQKIIFLTETTNQKAELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESEIVNQIIEQLISKERIYLSWVPAHK
GIGGNEQVDKLVSSGIRKVL

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D6E, E10D, K14R, D25E, V31I, K34R, M50I, I72V, I84M, F100W, L101I, T112V, T124A, T125A, K136Q, V201I, L234I S283G
>08_LH08| codons 1-288
FLDGIEKAQDEHERYHSNWRAMASEFNLPPIVAREIVASCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYMEAEVIPAETGQETAYWILKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

References
Author Title Citation
Manak, M Pilot studies for development of an HIV subtype panel for surveillance of global diversity. ARHR, 2012