<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    S17N, L45Q, S57N, I72V, I84L, S119T, T124A, K136Q, V201I, A205S, K211R, T218I, L234V, N254Q, S255G, D256E, I257L S283G
>44_LH01| codons 1-288
FLDGIDKAQEEHEKYHNNWRAMASDFNLPPVVAKEIVASCDKCQQKGEAMHGQVDCNPGI
WQLDCTHLEGKVILVAVHVASGYLEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGTN
FTSATVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIISTDIQTRELQKQIIKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDQGELKVVPRRKAKIIRDYGKQMAGDDCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12N, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, I72V, I93L  
>44_LH01| codons 1-99
PQITLWQRPLVNIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
DILIEICGHKAVGTVLVGPTPVNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, T39I, D123E, I135V, E138A, I142T, E169D, R172K, K173A, Q174K, I180V, Q207E, F214L, A272P, K277R, A288S, E297T, Q334D, M357T, I375V, K385R, E399D, A400I, V435I, A446S, T450N, L452K, V466A, S468P, T470S, D471E, T477A, H483Q, L491S, S519N, A534S, A554T, V559I  
>44_LH01| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICIEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSVNNATPGTRYQYNVLPQGWKGSPAIFQSSMTKILDPFKAKNPDIVV
YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKSLTEVIPLTTEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGDGQWTYQIYQEPFKNLKTGKYARTRGA
HTNDVKQLTEAVQKVATESIVIWGRTPKFKLPIQKETWDIWWTEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIIGAETFYVDGASNRENKKGKAGYVTDRGRQKAVPLSETTNQKAELQ
AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKEKVYLSWVPAHK
GIGGNEQVDKLVSTGIRKIL

References
Author Title Citation
Manak, M Pilot studies for development of an HIV subtype panel for surveillance of global diversity. ARHR, 2012