<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    D6E, E10D, E11D, K14R, S24N, D25E, V31I, M50I, L74I, L101I, K111R, T112V, T124A, K136Q, G163E, K173R, V201I, L234I, V260I, D278A S283G
>18_LH01| codons 1-288
FLDGIEKAQDDHERYHSNWRAMANEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI
WQLDCTHLEGKIIIVAVHVASGYIEAEVIPAETGQETAYFILKLAGRWPVRVIHTDNGSN
FTSATVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIEQVRDQAEHLRTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVIPRRKAKIIRDYGKQMAGADCVAGRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, K20R, E35N, M36I, N37E, R41K, H69K, L89M, I93L  
>18_LH01| codons 1-99
PQITLWQRPLVSIKVGGQIREALLDTGADDTVLENIELPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36A, T39E, S48T, E53D, K122E, D123G, T200A, Q207V, R211K, V245Q, A272S, K277R, E291D, V292I, I293V, K311R, S322T, I329L, Q334N, G335D, F346Y, R356K, G359T, T377M, K385R, K390R, A400T, E404D, V435A, E449D, L452I, R461K, V466I, S468T, D471E, H483Q, L491S, E492Q, S519N, K527R, V531I, A554K  
>18_LH01| codons 1-560
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPDNPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRAKIEELRVHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCKLLRGTKALTDIVPLTEEAE
LELAENREILREPVHGVYYDPTKDLIAELQKQGNDQWTYQIYQEPYKNLKTGKYAKMRTA
HTNDVKQLTEAVQKIAMESIVIWGRTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGAETFYVDGAANRDTKIGKAGYVTDKGRQKIVTLTETTNQKTELQ
AIQLALQDSGSQVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIRKEKIYLAWVPAHK
GIGGNEQVDKLVSKGIRKVL

References
Author Title Citation
Manak, M Pilot studies for development of an HIV subtype panel for surveillance of global diversity. ARHR, 2012