<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 None NA

Integrase Sequence
INIMajorDRMs INIMinorDRMs Polys UnusualMuts
    E11D, K14R, S24N, V31I, L63I, L74I, E96D, L101I, T112V, T124A, T125A, G134N, I135V, K136T, V201I, T206S, L234I, R269K  
>79_LH01| codons 1-288
FLDGIDKAQEDHERYHSNWRAMANDFNLPPIVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQIDCTHLEGKIIIVAVHVASGYIEAEVIPAETGQDTAYFILKLAGRWPVKVIHTDNGSN
FTSAAVKAACWWANVTQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIIDIIASDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIKDYGKQMAGDDCVASRQDED

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15L, K20I, E35D, M36I, R41K, I64L, H69K, K70R, L89M  
>79_LH01| codons 1-99
PQITLWQRPLVTVKLGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILLEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        E6D, V35T, V90I, K122E, D123N, I135V, T139R, S162A, K173T, Q174K, D177E, I178M, T200A, Q207G, V245Q, E248N, T286A, E291D, V292I, I293V, P294T, E312D, S322A, I326V, G335D, R356K, M357K, G359A, A371V, I375V, S379G, I380V, V381I, K390R, T403Q, V435A, L452Q, D471E, T477S, Q480H, H483Y, L491S, K512R, L517M, S519N, Q524K, K527E, E529D, A534S, A554N, V559I A437R
>79_LH01| codons 1-560
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSVNNERPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRGHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKDPVHGVYYDPAKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRAA
HTNDVKQLTEVVQKVATEGVIIWGKTPKFRLPIQKETWEAWWQEYWQATWIPEWEFVNTP
PLVKLWYQLEKEPIAGRETFYVDGAANRETKQGKAGYVTDRGRQKVVSLTETTNQKSELH
AIYLALQDSGSEVNIVTDSQYALGIIQAQPDRSESEMVNQIIEKLIEKDKVYLSWVPAHK
GIGGNEQVDKLVSNGIRKIL

References
Author Title Citation
Manak, M Pilot studies for development of an HIV subtype panel for surveillance of global diversity. ARHR, 2012