<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
KF256 KF256 Ghana 2010 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70KR, M184V, L210W, T215Y K219N G190A A98G V35T, T39K, K43E, E44D, I94L, D123E, I135M, K173A, Q174K, D177E, V179I, V189VI, T200A, Q207E, H208Y, R211K, V245Q, E248DN  
>KF256| codons 1-266
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKELEEDGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGLPHPGGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIII
YQYVDDLYIASDLEIGQHRAKIEELREYLWKWGFYTPDNKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14S, G16E, K20I, E35N, M36I, R41K, H69K, L89M  
>KF256| codons 1-99
PQITLWQRPLVTVSIEGQLIEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Nii-Trebi, NI HIV-1 drug-resistance surveillance among treatment-experienced and -naive patients after the implementation of antiretroviral therapy in Ghana. PLoS ONE, 2013