<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   G190A   E6K, K11T, V35T, E36A, T39K, K43E, V60I, K122E, D123N, I135V, T139K, I142V, S162Y, F171Y, K173A, D177E, V179I, T200A, Q207A, V245Q, E248H  
>1520| codons 1-266
PISPIKTVPVTLKPGMDGPKVKQWPLTEEKIKALTAICKEMEEEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSVNNEKPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPYRAQNPEIII
YQYVDDLYVASDLEIGQHRAKIEELRAHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPHKDSWTVNDIQKLVGKLNW

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L10LFI T12TA, I13V, K14KR, I15IV, G16AE, K20KI, E35D, M36I, R41K, K45KR, R57RK, L63LP, H69K, K70KR, V82VI, L89M  
>1520| codons 1-99
PQITLWQRPIVAVRVEGQLIEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD
QIPIEICGKRAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Nii-Trebi, NI HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana. PLoS ONE, 2013