<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 ABC+DDI+LPV 52
2 ABC+DDI+LPV+NVP 82
3 3TC+AZT+LPV 158

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74LI, M184V, L210SW, T215Y K219N V106M, G190A A98G, F227L T39K, K43R, E44D, K64KR, V118VI, K122E, D123S, I142V, K173A, Q174K, D177E, T200A, I202IV, E203K, Q207E, H208Y, R211K, K223E, V245Q  
>609| codons 38-247
CKELERDGKISKIGPENPYNTPVFAIRKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHP
GGLKKKKSMTVLDVGDAYFSIPLDESFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRAKNPEIVIYQYVDDLYVASDLEIGQHRAKVKELREYLWKWGFYTP
DNKHQEEPPLLWMGYELHPDKWTVQPIQLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A, L90M G73GS, N83D, L89V L10I, V11L, I13AV, K20R, A22V, E35N, M36I, N37D, R41K, K55R, R57RK, I62V, L63P, H69K, A71IV, T91S, I93L  
>609| codons 4-99
TLWQRPILTVKIGGQLREVLLDTGADDTVLENIDLPGKWKPKIIGGIGGFVRVKQYDQVP
IEICGKKVISTVLVGPTPADIIGRNVMSQLGCTLNF

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014