<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+DDI+LPV 106
2 3TC+D4T+DDI+LPV 110

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184I, L210W, T215Y V75M, K219R   V108I E44D, V60I, V118I, K122E, Q174K, N175Y, V179VI, G196E, T200R, E203V, Q207E, R211A, D218E, L228V, Q242L I37L
>33| codons 37-247
LCTELEKDGKISKIGPENPYNTPIFAIKKKNSDKWRKLMDFRELNKRTQDFWEVQLGIPH
PAGLKKKKSVTILDVGDAYFSIPLDEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGS
PAIFQSSMTKILEPFRKKYPDIIIYQYIDDLYVGSDLEIEQHRRKIVELREHLWAWGFYT
PERKHQKEPPFVWMGYELHPDKWTVLPIVLP

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82T, I84V Q58E L10I, I15V, L19I, K20R, M36I, N37D, D60E, L63P, I85V, L89M P79G
>33| codons 4-99
TLWQRPIVTIKVGGQIREALLDTGADDTVLEEIDLPGRWKPKIIGGIGGFVKVREYEQIP
IEICGHKAIGTVLVGGTPTNVVGRNMLTQIGCTLNF

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014