<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 IDV|RTI NA
2 3TC+LPV+TDF 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A L10F I15V, K20R, E35ED, M36I, N37D, R41K, R57K, I62V, L63P, I64M, H69K, K70KQ, A71AV, I72IV, L89M, I93L  
>952| codons 4-99
TLWQRPFVTIKVGGQLREALLDTGADDTVLEDIDLPGKWKPKIIGGIGGFVKVKQYDQVP
MEICGKQVVGTVVVGPTPANIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219E Y181C, G190S   T39E, S48T, T69S, W88R, A98S, K101Q, K122E, D123S, I135T, Q174K, D177E, T200A, I202IV, Q207E, L228H, V245Q E79G
>952| codons 38-246
CEEMEKEGKITKIGPENPYNTPVFAIKKKNSSRWRKLVDFRGLNKRTQDFREVQLGIPHP
SGLQKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKKNPEIVICQYVDDLYVSSDLEIGQHRAKVEELREHLLRWGFFTP
DEKHQKEPPFHWMGYELHPDKWTVQPIQL

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014