<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 3TC+AZT+NVP 51

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   K20KR, V35T, I47L, K49KR, I50V, V60I, A98AS, K102KN, K122E, D123NS, I135T, E138Q, I142IV, K173S, Q174K, D177E, V179I, E194D, T200A, Q207A, R211S, F214FL, V245E, T286A, I293V, P294T, E312D, I326IT  
>468H| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKLSRVGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKNNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNQTPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII
YQYVDDLYVGSDLDIGQHRAKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEVVTLTEEAE
LELAENREILKDPVHGVYYDPSKDLTAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, K20KI, E35D, M36I, R41K, R57K, L63H, E65ED, H69K, K70KR, L89M  
>468H| codons 1-99
PQITLWQRPVVTVKIEGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QIHIDICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Rusine, J Low primary and secondary HIV drug-resistance after 12 months of antiretroviral therapy in human immune-deficiency virus type 1 (HIV-1)-infected individuals from Kigali, Rwanda. PLoS ONE, 2013