Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA1131 | CA2579 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | NA |
| 2 | 3TC+D4T+SQV | NA |
| 3 | Unknown | NA |
| 4 | None | 143 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14KR, I15V, L19LQ, N37C, R41X, V82I |
| >CA2579| codons 1-99 PQITLWQRPLVTIRVGGQQKEALLDTGADDTVLEEMCLPGXWKPKMIGGIGGFIKVRQYD QILIEICGHKAIGTVLVGPTPINIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N | T215V, K219Q | K20KR, V35I, V60I, V118I, K122E, I135T, Q174N, Q207E, R211K, F214L, V245X |
| >CA2578| codons 1-253 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKNNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGLVTPDQKHQKEPPFLWMGYELHPDKWT VQPIXLPEKDSWT |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |