<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82IM L24I L10I, I13V, K14R, L19I, K20I, E35Q, M36I, N37D, R41K, R57K, Q61QH, L63P, I64M, C67E, H69K, K70R, L89M  
>PJ9611| codons 1-99
PQITLWQRPIVTVRIGGQIIEALIDTGADDTVLEQIDLPGKWKPKMIGGIGGFVKVKQYD
HIPMEIEGKRAIGTVLVGPTPMNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y   K103KN A98G, V108VI V35T, V60I, L109LI, D121HY, K122E, I135T, K173T, Q174R, D177E, T200A, I202V, Q207D, R211K, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292I, I293V, I329V  
>PJ9611| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSVTIIDVGDAYFSVPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPEIVI
YQYVDDLYVGSDLEIGQHRAKVEELRDHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQG

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013