<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V   L10LI, T12A, I13V, K14R, K20I, E35Q, M36I, N37D, R41K, K45R, R57K, C67E, H69K, V82I, L89M  
>PJ5683| codons 1-99
PQITLWQRPIVAVRIGGQLIEALLDTGADDTVLEQIDLPGKWKPRMIGGIGGFVKVKQYD
QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, K70R, M184V, T215F D67G, K219Q Y181C   I31L, V35T, T39A, K49R, V60I, K173T, Q174R, D177E, I178M, T200A, Q207E, R211K, L228R, V245Q, E248D, D250E, S251D, A272P, K277R, T286A, E291D, V292I, I293V, D324E  
>PJ5683| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTEICAELEKEGKISRIGPENPYNTPI
FAIKKKGSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTRNPEMVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFFTPDQKHQKEPPFRWMGYELHPDKWT
VQPIQLPDKEDWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKELIAEIQKQG

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013