<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, G48V, L90M L33F, N83D L10V, I13V, K20R, E35DN, M36I, N37E, P39Q, R41K, D60E, Q61E, H69K, L89IM  
>LL0499| codons 1-99
PQITLWQRPVVTVKIGGQLREALLDTGADDTVFENIELQGKWKPKLIVGIGGFIKVRQYE
EILIEICGKKAIGTVLVGPTPVDIIGRNMMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R, M184V D67G, K219Q Y181C   K11T, K20R, V35T, T39S, V60I, T69N, D121Y, K122E, I135T, T139R, E169D, K173A, Q174K, D177E, V179I, G196E, T200A, E203V, Q207A, R211K, F214L, L228H, Q242H, D250E, A272P, L283I, E291D, I293V, E312D, Q334E  
>LL0499| codons 1-335
PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICSEMEKEGKISKIGPENPYNTPI
FAIKKKGSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSTNNERPGIRYQYNVLPQGWKGSPAIFQSSMTKILDPFRAKNPEIII
CQYVDDLYVGSDLEIEQHRAKIVELRAHLLKWGLTTPDQKHQKEPPFHWMGYELHPDKWT
VHPIVLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLIRGTKALTDVVPLTEEAE
LELAENREILKDPVHGVYYDPSKDLIAEIQKQGEG

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013