<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, L76LV   I13A, K14R, G16E, K20I, M36I, P39A, R41K, I62V, L63S, H69K, K70R, L89I  
>PJ9581| codons 1-99
PQITLWQRPLVTARIEGQLIEALLDTGADDTVLEEINLAGKWKPKIIGGIGGFIKVRQYD
QVSIEICGKRAIGTVVVGPTPVNIIGRNILTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Q151M, M184V F116Y K103N, Y181C   K20R, E28D, K32KQ, V35K, E36D, T39A, S68G, K101R, D123E, I135T, S162A, T165I, E169D, K173T, Q174K, D177E, G196E, T200A, Q207E, F214L, V245Q, K281R, T286A, E291D, V292I, I293V, P294T, S322T, I326V  
>PJ9581| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTDEKIQALKDICAEMEKEGKISKIGPENPYNTPV
FAIKRKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKNKSVTVLDVGDAYYSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPMGWKGSPAIFQASMIKILDPFRTKNPEIVI
CQYVDDLYVGSDLEIEQHRAKIEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLVAEIQKQGQ

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013