<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215F     A98G V35T, E36D, K49R, D123E, I135T, A158S, S162A, K173A, Q174K, D177E, T200A, E203V, Q207E, R211K, V245E, T286A, E291D, I293V, P294T, S322T  
>LN8580| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTELEKEGKISRIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPSIFQASMTKILEPFRAKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIVELREHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82VA, I84IV L89V L10LI, I13V, G16A, K20I, M36I, R41K, H69K, K70R, A71AV  
>LN8580| codons 1-99
PQITLWQRPIVTVKIAGQLIEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFVKVRQYD
QILIEICGKRVIGTVVVGPTPANVIGRNVLTQIGCTLNF

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013