<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46ML, G48V, I54V, V82ST K43KT L10I, I13V, I15IV, L19I, K20I, M36I, R41K, Q61DE, I64M, C67S, H69K, A71V, L89M, I93M  
>LM8689| codons 1-99
PQITLWQRPIVTVKVGGQIIEALLDTGADDTVLEEINLPGKWTPKLIVGIGGFVKVRQYD
EILMEISGKKVIGTVLVGPTPTNIIGRNMLTQMGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74LV, M184V, L210W, T215Y       K20R, V35IT, T39DN, E40X, K43KE, K122E, I135IATV, K173A, Q174K, D177E, I178M, I195L, T200A, Q207E, R211K, V245Q, D250E, A272P, Q278H, T286A, A288T, E291D, V292I, I293V, E297A, L301M, D320E, D324E, I329V  
>LM8689| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICNXLEEEGKISKIGPENPYNTPV
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEMVI
YQYVDDLYVGSDLELGQHRAKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKHLCKLLRGAKTLTDIVPLTAEAE
MELAENREILKEPVHGVYYEPSKELIAEVQKQG

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013