<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, L210W, T215Y   Y181C, G190A A98G V21I, V35T, E44D, T69N, W88C, V111I, V118I, K122E, K173A, Q174K, D177E, T200A, E203K, Q207D, H208Y, R211RK, K223E, L228R, P243PS, V245Q, E248D, A272S, T286A, A288S, V292I, I293V, I329V  
>PJ6749| codons 1-333
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICTELEKDGKISKIGPENPYNTPV
FAIKKKDSNKWRKLVDFRELNKRTQDFCEVQLGIPHPGGLKKKKSVTVLDIGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
CQYVDDLYVASDLEIGQHRAKIKELRDYLWKWGFYTPDKKHQEEPPFRWMGYELHPDKWT
VQSIQLPDKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKSLTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEVQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L, G48Q, I54V, L76V, I84V F53L L10V, I13A, K14R, I15V, K20I, M36I, R41K, K55R, R57K, Q61HN, I64V, C67E, H69K, T74S, L89I, T91A E35H
>PJ6749| codons 1-99
PQITLWQRPVVTARVGGQLIEALLDTGADDTVLEHINLPGKWKPKLIQGIGGLVRVKQYD
NILVEIEGKKAIGSVVVGPTPVNVIGRNILAQIGCTLNF

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013