<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, V82A L10F, Q58E I13V, I15V, G16E, K20I, E35D, M36I, R41K, L63R, I64M, H69K, K70R, L89M, T91A  
>LL5309| codons 1-99
PQITLWQRPFVTVKVEGQLIEALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVREYD
QIRMEICGKRAIGTVVVGPTPANIIGRNMLAQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T215Y   K103N   T7TP, E28K, K32E, L34I, V35T, T39X, V60I, V90VI, V118I, D121H, K122E, I142V, Q174S, D177E, I178F, G196E, T200A, E203D, Q207D, H208Y, R211K, L228LIM, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, I293V, E297T, V317A, S322T  
>LL5309| codons 1-335
PISPIEPVPVKLKPGMDGPKVKQWPLTKEKIEAITEICXELEKEGKISKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
HEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKSNPEFVI
YQYMDDLYVGSDLEIEQHRAKIDELRDYLLKWGFYTPDKKHQKEPPFMWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDVVPLTTEAE
LELAENREILKEPVHGAYYDPTKDLIAEIQKQGQG

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013