<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82S L24I, K43T L10V, I13V, K14R, G16GA, K20I, E35D, M36I, R41K, R57K, I62V, L63P, C67E, H69R, I72V, T74A, L89M  
>LN0609| codons 1-99
PQITLWQRPVVTVRIAGQLIEALIDTGADDTVLEDINLPGKWTPKIIGGIGGFVKVKQYD
QVPIEIEGRKAVGAVLVGPTPSNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Q151M A62V, V75I, F77L, F116Y Y181C, G190A   P4T, K20KR, K22R, I31L, V35T, T39K, E40D, T58N, S68G, V90I, V118I, K122E, T165I, K173A, Q174R, D177E, T200A, L205F, Q207E, R211K, F214L, V245Q, E248D, D250E, S251H, A272P, Q278H, K281R, T286A, E291D, V292I, I293V, E297A, L301M, I329V  
>LN0609| codons 1-333
PISTIETVPVKLKPGMDGPRVRQWPLTEEKLKALTEICKDMEKEGKISKIGPENPYNNPV
FVIKKKDGTKWRKLIDLRELNKRTQDFWEIQLGIPHPAGLKKKKSVTVLDVGDAYYSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMIKILEPFRARNPEIVI
CQYMDDLYVASDLEIGQHRAKIEEFREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKEHWTVNDIQKLVGKLNWASQIYPGIKVKHLCRLLRGAKALTDIVPLTAEAE
MELAENREILKEPVHGVYYDPSKDLIAEVQKQG

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013