<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46LV, I54V, L76V, V82M, L90M L89IV T4S, L10IV, I13A, K20IV, A22V, E35D, M36I, N37DE, Q61E, I62V, L63P, C67F, H69K, A71I, I72L, P79A, T91S, Q92QK  
>PJ2149| codons 1-99
PQISLWQRPVVTAKIGGQLVEVLLDTGADDTVLEDIELPGRWKPKVIGGIGGFVKVRQYD
EVPIEIFGKKILGTVVVGATPMNIIGRNVMSKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, K70R, M184V, L210W, T215F V75M, K219Q K101E, Y181C, G190A   K20R, K32KR, V35T, K43N, V60I, V111I, V118I, K122E, I142V, S162D, Q174K, D177E, I178M, V179M, V189I, T200A, E203D, Q207DE, H208Y, R211K, D218E, L228H, P243T, V245Q, E248D, T286A, E291D, V292I, I293V, E297A  
>PJ2149| codons 1-335
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIRALTEICTELENEGKISKIGPENPYNTPI
FAIKKKNSDRWRKLMDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDIGDAYFSIPL
DEDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQDSMTKILEPFRKKNPEMMI
CQYVDDLYIASDLEIGQHRAKIDELREYLWKWGFFTPEQKHQKEPPFHWMGYELHPDKWT
VQTIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013