<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219E Y181C V108VI P4S, T27S, V35T, T39K, K43A, T69TN, V90I, K102Q, V111I, D123E, I142V, S162Y, K173S, D177DE, V179I, T200A, Q207A, R211K, P243PS, V245T, E248D, T286A, E291D, I293V, P294PT  
>LM3929| codons 1-334
PISSIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICKEMEAEGKISKIGPENPYNTPV
FAIKKKNSNRWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKQKKSVTILDIGDAYFSVPL
DKEFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQYSMTKILEPFRSQNPEIII
CQYVDDLYVGSDLEIGQHRAKIEELRAHLLKWGFFTPDEKHQKEPPFLWMGYELHPDKWT
VQSITLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, V82A F53L, Q58E L10I, I13V, K14R, I15V, K20I, L33L_L, E35G, M36I, R41K, K55R, L63T, I64M, L89M  
>LM3929| codons 1-99
PQITLWQRPIVTVRVGGQLIEALLDTGADDTVLEGINLPGKWKPKIVGGIGGLVRVREYD
QITMEICGHKAIGTVLVGPTPANIIGRNMLTQIGCTLNF

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013