<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, K70R, M184V, L210W, T215F D67G Y181I   I31L, V35T, E36A, T39A, K43E, V118VI, K122KE, S162A, K173I, Q174K, D177E, I178M, V179I, G196E, T200A, E203V, Q207E, V245E, T286A, E291D, V292I, I293V, P294T, S322T  
>PJ9959| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKLKALTAICAELEEEGKISKIGPENPYNTPV
FAIKKKGSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRIKNPEMII
IQYVDDLYVGSDLEIEQHRAKIVELREHLWRWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE
LELAENREILKEPVHGVYYDPTKDLIAEIQKQGQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A   L10I, I13V, K14R, G17E, K20I, M36I, N37S, R41K, C67H, H69K, L89M P81PL
>PJ9959| codons 1-99
PQITLWQRPIVTVRIGEQLIEALLDTGADDTVLEEISLPGKWKPKIIGGIGGFVKVRQYD
QILIEIHGKKAIGTVLVGPTLANIIGRNMLTQIGCTLNF

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013