<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82F Q58E, N83D L10V, T12M, I13A, K14KR, G16A, L19P, K20I, A22V, E35N, M36I, N37D, R41RK, Q61QH, L63P, H69K, A71V, L89I, I93M  
>LN4321| codons 1-99
PQITLWQRPVVMARIAGQPIEVLLDTGADDTVLENIDLPGKWKPKMIGGIGGFVKVREYD
HIPIEICGKKVIGTVLVGPTPFDIIGRNILTQMGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Y115F, Q151M, M184V A62V, V75I, F77L, F116Y, K219E Y181C   K20R, V35T, S68G, T69I, I135V, S162A, K173T, Q174K, D177E, I178L, T200A, Q207E, R211K, F214L, V245E, S251H, T286A, E291D, V292I, I293V, P294T, E297K, K311R, S322T, I326V  
>LN4321| codons 1-334
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV
FVIKRKDGIKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFYSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQASMTKILEPFRTKNPELVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT
VQPIELPEKDHWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTKEAE
LELAENREILREPVHGVYYDPTKDLVAEIQKQGQ

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013