<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12A, I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, K43R, L63P, H69K, L89M  
>LL5290| codons 1-99
PQITLWQRPLVAVRVGGQLIEALLDTGADDTVLEDIDLPGKWRPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41ML, M184V, L210L*W, T215Y   G190A   V35T, E36D, I47IL, K49R, V60I, I135IV, K173T, Q174K, D177E, V179IL, E194ED, Q207D, R211K, V245Q, E248ED, D250E, S251D, A272AP, T286A, E291D, I293V, P294T  
>LL5290| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICTELEKEGKLSRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEILI
YQYVDDLYVASDLDIGQHRTKIEELRDHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKEDWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQ

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013