<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A   I13V, G17E, K20I, M36I, N37N_N, R41K, I62V, E65Q, H69K, L89M  
>LN6209| codons 1-99
PQITLWQRPLVTVKIGEQLIEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFVKVRQYD
QVLIQICGKKAIGTVLVGPTPANIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K70R       V35T, V60I, K64R, D121H, K122E, D123S, I135V, F171Y, K173AV, Q174K, D177E, I178L, T200E, Q207K, R211Q, V245Q, K275Q, K277R, T286A, E291D, V292I, I293V, P294I, E297K, E312G  
>LN6209| codons 1-334
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI
FAIRKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPYRVKNPELVI
YQYMDDLYVGSDLEIGQHREKIEELRKHLLQWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIQVRQLCKLLRGAKALTDIVILTKEAE
LELAENREILKGPVHGVYYDPSKDLIAEIQKQGQ

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013