<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 LPV+NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
Y115F, Q151M, M184V A62V, V75I, F77L, F116Y, K219E K103N V108I, K238T P14A, D17DE, V35T, E36D, E40K, K43Q, K46Q, K49R, T58N, S68G, K122E, D123N, I135IV, S162T, K173T, Q174K, D177E, I178IM, T200A, E203EK, Q207E, R211K, V245E, A272P, Q278N, L283I, E291D, V292I, I293V, P294A, S322T, D324E I244IT
>PJ9681| codons 1-334
PISPIETVPVKLKAGMEGPKVKQWPLTEEKIKALTDICTKMEQEGQISRIGPENPYNNPV
FVIKKKDGTKWRKLIDLRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAFYSVPL
DENFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQTSMTKILEPFRTKNPEMVI
YQYVDDLYVGSDLEIGQHRAKIKELREHLLKWGFTTPDEKHQKEPPFLWMGYELHPDTWT
VQPTELPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKNLCKLIRGTKALTDIVALTEEAE
LELAENREILKEPVHGVYYDPTKELIAEIQKQGQ

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82A L89V L10V, I13A, K14R, I15V, K20I, A22V, E35D, M36I, R41K, Q61H, L63P, H69K  
>PJ9681| codons 1-99
PQITLWQRPVVTARVGGQLIEVLLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD
HIPIEICGKKAIGTVLVGPTPANIIGRNVLTQIGCTLNF

References
Author Title Citation
Rawizza, HE Accumulation of protease mutations among patients failing second-line antiretroviral therapy and response to salvage therapy in Nigeria. PLoS ONE, 2013