<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   G190A   V35T, T39L, V60I, D121Y, K122E, I135V, D177E, I178M, V179I, Q197K, T200A, Q207G, R211K, D237E, V245K, D250E, S251N, A272P, I274V, V276T, K277R, L282C, T286A, E297A L283V
>JCR022_0| codons 1-307
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMII
YQYVDDLYVASDLEIGKHRAKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPEKWT
VQPIKLPEKENWTVNDIQKLVGKLNWASQIYPGVKTRQLCKCVRGAKALTEVIPLTAEAE
LELAENR

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K20M, E35N, M36I, R41K, I64V, H69Q  
>JCR022_0| codons 1-99
PQITLWQRPLVTVKIGGQLMEALLDTGADDTVLENINLPGKWKPKMIGGIGGFIKVRQYD
QILVEICGQKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013