<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, T69D, M184V, T215Y   K103N, M230L V108I V35T, K43E, E44A, V60I, V111I, V118I, K122E, D123S, K173L, Q174K, D177E, V189I, T200A, R206K, Q207A, L210S, R211S, L228R, V245E, A272P, K275Q, K277R, T286A, E291D, I293V, P294T, E297K T216M
>MBA079_0| codons 1-312
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEEAGKISKIGPENPYNTPI
FAIKKKDSDKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDIGDAYFSIPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRLKNPEIVI
YQYVDDLYIGSDLEIGQHRAKIEELKAHLSSWGFYMPDKKHQKEPPFRWLGYELHPDKWT
VQPIELPEKDSWTVNDIQKLVGKLNWASQIYPGIQVRQLCKLLRGAKALTDVVTLTKEAE
LELAENREILKE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, T12I, I13V, E35D, M36I, R41K, R57K, I62V, L63P, I64L, H69K, L89M  
>MBA079_0| codons 1-99
PQITLWQRPIVIVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QVPLEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013