<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
T69D, K70R, M184V   Y181C   V21I, V35T, T39S, K49R, V60I, D121Y, K122E, I135M, I142V, S162N, K166R, D177E, I178M, T200A, Q207E, R211K, L228R, V245K, D250E, A272P, K277R, L282C, T286A, I293V, E297A  
>JCR073_0| codons 1-305
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICSEMEKEGKISRIGPENPYNTPI
FAIKKKDSDRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSMNNETPGVRYQYNVLPQGWKGSPAIFQNSMTRILEPFRKQNPEMVI
CQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFTTPDKKHQKEPPFRWMGYELHPDKWT
VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCLRGAKALTEVVPLTAEAE
LELAE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33I I13V, M36T, R41K, D60E, I62V, L63V, I64V, E65D, K70R  
>JCR073_0| codons 4-99
TLWQRPLVTVKIGGQLKEALLDTGADDTVIEETNLPGKWKPKMIGGIGGFIKVRQYEQVV
VDICGHRAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013