<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, L210W, T215Y V75VL G190A A98G E6N, K11Q, V35T, E44D, K49R, V60I, I94L, K101Q, D121Y, K122E, I135M, T165I, D177E, Q207E, R211K, V245Q, L282C, L283I, K287R, I293V V111IM
>JCR113_0| codons 1-306
PISPINTVPVQLKPGMDGPKVKQWPLTEEKIKALTEICTELEKDGKISRIGPENPYNTPI
FAIKKKNSTKWRKLLDFRELNKRTQDFWEVQLGLPHPGGLQKKKSVTVLDMGDAYFSVPL
YEDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMIKILEPFRKQNPEIVI
YQYVDDLYVASDLEIGQHRTKIEELREHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKCIRGTRALTEVVPLTEEAE
LELAEN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, M36I, R41K, I62V, L63A  
>JCR113_0| codons 1-99
PQITLWQRPVVTVKIGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QVAIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013