<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215Y   K103N   V35T, T39K, S48T, K49R, V60I, A98S, D121Y, K122E, I135T, D177E, I178M, T200A, Q207E, R211K, V245K, E248D, A272P, K277R, K281R, L282C, T286A, I293V, I309L  
>JCR093_0| codons 1-309
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKITRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEMVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCRCLRGAKALTEVVPLTEEAE
LELAENREL

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G17E, Q18*, N37S, P39S, R41K, D60E, I62V, L63P, I64V, K70R, V77I  
>JCR093_0| codons 1-99
PQITLWQRPVVTVKIGE*LKEALLDTGADDTVLEEMSLSGKWKPKMIGGIGGFIKVRQYE
QVPVEICGHRAIGTVLIGPTPVNIIGRNLLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013