<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V K219Q G190A   E6D, K20R, V35T, E40D, E42K, K43R, K46R, V60I, K122E, D123N, I135T, E138A, K173S, Q174K, D177E, V179I, T200A, I202V, E203K, Q207D, R211K, V245Q, E248D, D250E, T286A, E291D, I293V, P294T, E312D  
>JCR070_0| codons 1-315
PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICTDMKREGRISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII
YQYVDDLYVASDLEIGQHRAKVKELRDHLLKWGFTTPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVTLTEEAE
LELAENREILKDPVH

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10I, I13V, G16E, G17X, E35D, M36I, P39S, R41K, H69K, K70R, L89M  
>JCR070_0| codons 1-99
PQITLWQRPIVTVKIEXQLKEALLDTGADDTVLEDINLSGKWKPKMIGGIGGFIKVRQYD
QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013