<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, T215F K219E G190A   K11T, K20R, V35T, T39N, K43R, E44D, V60I, T69N, K102Q, K122E, D123S, E138Q, S162A, K173T, D177E, I178F, V179I, G196K, T200K, E203D, Q207A, R211K, L228H, V245Q, E248D, K259KR, K277R, Q278H, E291D, V292I, I293V, E312K  
>JFP048_0| codons 1-312
PISPIETVPVTLKPGMDGPRVKQWPLTEEKIKALTEICNELERDGKISKIGPENPYNTPI
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNQTPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTQNPEFII
YQYVDDLYVASDLEIKQHRKKIDELRAHLLKWGFFTPDEKHQKEPPFHWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQRLVGKLNWASQIYAGIKVRHLCKLLRGTKALTDIVPLTEEAE
LELAENREILKK

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, G16E, K20R, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89M  
>JFP048_0| codons 1-99
PQITLWQRPVVTVKIEGQLREALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD
QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013