Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| JCR099_0 | JCR099_0 | Uganda | 2010 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Y115F | Y181C | P4T, E28K, V35T, E40ED, V60I, V118I, I135T, I142V, A158S, K173E, D177E, Q207E, R211K, F214L, V245E, D250E, A272S, K275R, L282C, I293V | R72K, P243K |
| >JCR099_0| codons 1-307 PISTIETVPVKLKPGMDGPKVKQWPLTKEKIKALTEICTDMEKEGKISKIGPENPYNTPI FAIKRKDSTKWKKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAFFSIPL DKDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPSIFQSSMTKILEPFREQNPEIVI CQYMDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQKIELPEKESWTVNDIQKLVGKLNWASQIYSGIRVKQLCKCLRGTKALTEVVPLTEEAE LELAENR |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, G16E, E35D, M36I, P39S, R41K, I62V, L63S, I64V, E65D |
| >JCR099_0| codons 1-99 PQITLWQRPVVTVKIEGQLKEALLDTGADDTVLEDINLSGKWKPKMIGGIGGFIKVRQYD QVSVDICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Sigaloff, KC | Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. | ARHR, 2013 |