<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, M184V, T215Y V75M K101E, K103N, G190A   K20R, T27S, E28A, V35T, E44ED, V60I, K122E, D123S, I135T, I142Q, K173S, Q174K, D192N, T200A, E203K, Q207D, R211K, V245T, D250E, A272P, T286A, E291D, V292I, I293V  
>MBA005_0| codons 1-306
PISPIETVPVKLKPGMDGPRVKQWPLSAEKIKALTEICTELEKDGKISKIGPENPYNTPI
FAIKKKNSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLEKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGQRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPDIVI
YQYVDDLYVASNLEIGQHRAKIKELRDHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPITLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAEN

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I3N, E35D, M36I, N37E, R41K, R57K, D60E, H69K, L89M  
>MBA005_0| codons 1-99
PQNTLWQRPLVTIKIGGQLKEALLDTGADDTVLEDIELPGKWKPKMIGGIGGFIKVKQYE
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013