<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215F   K101E, G190A   K20R, V21I, E28K, V35T, T39S, V60I, K122E, D123N, I135T, Q145V, K173A, D177E, V179I, T200A, I202V, Q207AT, R211K, V245Q, E248D, A272P, T286A, E291D, P294T, E297K  
>JCR120_0| codons 1-309
PISPIETVPVKLKPGMDGPRIKQWPLTKEKIKALTEICSEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYVYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIII
YQYVDDLYVASDLEIGQHRAKVEELRTHLLKWGFFTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDVITLTKEAE
LELAENREI

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, T12A, I13V, K14R, G16E, K20I, M36I, N37S, R41K, Q61E, L63S, H69K, I72T, L89M  
>JCR120_0| codons 1-99
PQITLWQRPVVAVRIEGQLIEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD
EISIEICGKKATGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013