Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| MBA036_0 | MBA036_0 | Uganda | 2010 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NNRTI+NRTI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | P225H, K238T | V35T, V60I, I142V, S162C, D177E, I178M, Q197E, T200K, Q207K, R211K, V245K, D250E, A272P, K275R, K277R, Q278H, L282C, L283I, I293V |
| >MBA036_0| codons 1-306 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEMVI YQYVDDLYVGSDLEIGEHRKKIEELRKHLLKWGFTTPDKKHQKEHPFLWMGYELHPDTWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIRVRHLCKCIRGTKALTEVVPLTEEAE LELAEN |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10V, I13V, M36I, R41K, L63P, I64V |
| >MBA036_0| codons 1-99 PQITLWQRPVVTVKIGGQLKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPVEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Sigaloff, KC | Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. | ARHR, 2013 |