<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, Y115F, M184V   Y181I   E6D, V35T, T39K, V60I, W88C, K122E, D123G, K173S, Q174K, D177E, V179I, T200A, Q207A, F214L, V245E, D250E, I257L, V261I, T286A, E291D, I293V, K311R  
>JCR104_0| codons 1-314
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFCEVQLGIPHPAGLKKKKSVTVLDVGDAFFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII
IQYVDDLYVGSDLEIGQHRAKIEELRAHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIELPEKESWTVNDLQKLIGKLNWASQIYAGIKVKQLCKLLRGAKALTDVVPLTEEAE
LELAENREILREPV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L5F, I13V, I15V, E35D, M36I, R41K, R57K, L63P, H69K, L89M  
>JCR104_0| codons 1-99
PQITFWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013