<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N P225H E6D, V35T, E40D, V60I, V118I, K122E, D123S, I135T, T165L, K173A, Q174N, D177E, T200TA, Q207A, R211S, F214L, V245E, D250E, A272P, K277R, K281R, T286A, E291D, I293V  
>MBA054_0| codons 1-307
PISPIDTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMLKILEPFRANNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRAHLLSWGLTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIELPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCRLLRGAKALTDVVPLTEEAE
LELAENR

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I3N, I13V, E35D, M36I, R41K, R57K, D60E, H69K, L89M  
>MBA054_0| codons 1-99
PQNTLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013