<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 NNRTI+NRTI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R, M184V, T215F K219E Y188L   K11T, K20R, V21I, V35T, T39R, K43E, T69N, V106L, L109I, K122E, D123N, K173A, Q174K, D177E, V179I, I202V, Q207A, R211S, K238E, V245Q, E248D, K281R, T286A, E291D, V292I, I293V, P294T, E297K  
>MBA063_0| codons 1-314
PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICREMEEEGKISKIGPENPYNTPV
FAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSLTVIDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIII
YQYVDDLLVGSDLEIGQHRTKVEELRAHLLSWGFFTPDEKHQKEPPFLWMGYELHPDEWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVTLTKEAE
LELAENREILKEPV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    G16E, K20R, E35D, M36I, R41K, R57K, L63S, H69K, L89M  
>MBA063_0| codons 14-99
KIEGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYDQISIEICGKKAIG
TVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Sigaloff, KC Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. ARHR, 2013