<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TH_189 TH_189 Thailand 2001 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ AZT NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, I15V, E35D, M36I, R41K, L63S, H69K, V82I, L89M  
>TH_189| codons 1-99
PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QISIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D K219Q     V21I, V35T, T39K, K43E, V60I, K122E, D123S, K173I, Q174K, D177E, I178M, G196E, T200I, Q207A, R211S, K238R, V245E  
>TH_189| codons 17-252
DGPKIKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPIFAIKKKNSDKWRKLVD
FRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSIN
NETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEMVIYQYMDDLYVGSDLEIE
QHRIKIEELRAHLLSWGFTTPDQKHQKEPPFLWMGYELHPDRWTVQPIELPEKDSW

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005