<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TH_130 TH_130 Thailand 2001 HIV1 CRF01_AE Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ RTV+ AZT+ 3TC NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, E35D, M36I, R41K, H69K, V82I, L89M  
>TH_130| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, T69D, K70R, L74I, T215F K219Q     V35T, T39K, K43E, V60I, K122E, D123S, K173T, Q174K, D177E, I178M, Q207A, R211S, K238R, V245K  
>TH_130| codons 19-253
PKVKQWPLTEEKIKALTEICKEMEEEGKISKIGPENPYNTPIFAIKKKNSDRWRKIVDFR
ELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSINNE
TPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEMVIYQYMDDLYVGSDLEIGQH
RTKIEELRAHLLSWGFFTPDQKHQKEPPFLWMGYELHPDRWTVQPIKLPEKDSWT

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005