<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|SQV NA
2 D4T+DDI+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
D30N N88D T12V, L19I, K20I, M36I, R41K, K45R, L63T, H69K, A71V, I93L  
>160| codons 4-99
TLWQRPLVVIKIGGQIIEALLDTGADNTVLEEINLPGKWKPRMIGGIGGFIKVRQYDQIT
IEICGKKVIGTVLVGPTPVNIIGRDLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L210W, T215Y   K103N, G190A   T39E, K43Q, E44A, K49R, V60I, K101Q, K102Q, K122E, D123S, A158S, E169A, K173A, Q174K, D177E, T200A, Q207E, R211K, V245Q R125S
>160| codons 38-247
CEELEQAGKISRIGPENPYNTPIFAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLQQNKSVTVLDVGDAYFSVPLDESFSKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
SIFQSSMTKILAPFRAKNPEIVIYQYMDDLYVASDLEIGQHRAKIEELREHLWKWGFYTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014