<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 IDV|NFV|RTI|RTV NA
2 ABC+D4T+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54IV, V82A, I84IV   L10I, T12S, I15V, K20M, E34K, M36I, R41K, L63V, H69K, T74S, L89M, I93L  
>789| codons 4-99
TLWQRPIVSIKVGGQLMEALLDTGADDTVLKEINLPGKWKPKMIGGIGGFVKVRQYDQIV
IEICGKKAIGSVLVGPTPANVIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70R T215V, K219E Y188YH   T39E, S48T, V60I, T69N, A98S, K122E, D123S, I135T, K166R, K173A, D177E, T200A, Q207E, R211K, V245Q K102LMST
>789| codons 38-247
CEEMEKEGKITKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLKTKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTRILEPFRAQNPEIVIYQYMDDLHVGSDLEIGQHRAKIEELREHLLKWGFVTP
DEKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014