<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 IDV|RTI NA
2 ABC+DDI+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L10F I13X, I15V, K20T, M36I, R41K, I62IV, L63P, H69K, T74S, L89M, I93L  
>155| codons 4-99
TLWQRPFVTXKVGGQLTEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFVKVRQYDQVP
IEICGKKAIGSVLVGPTPANIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74LV, M184V T215TN Y181C V108I T39D, K49R, K101R, K122E, D123S, K166R, K173A, Q174N, D177E, V179I, T200A, Q207E, R211K, H221Y, V245Q  
>155| codons 38-247
CDEMEKEGKISRIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLRKKKSVTILDVGDAYFSVPLDESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTRILEPFRANNPEIIICQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFNTP
DKKYQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014