<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|SQV NA
2 3TC+DDC+LPV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, V82A L10F, L33F L19Q, K20R, E35D, M36I, N37ND, P39Q, R41K, I62IV, L63P, H69K, L89M, Q92QK, I93L G27GR
>852| codons 4-99
TLWQRPFVTIKIGGQQREALLDTRADDTVFEDIDLQGKWKPKIIGGIGGFVKVRQYDQVP
IEICGKKAIGTVLVGPTPANIIGRNMLTKLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V, T215Y       T39E, S48T, K102Q, K122E, D123S, I135V, S162C, K173A, Q174K, D177E, I178L, T200A, Q207E, V245Q F61FS
>852| codons 38-247
CEELEKEGKITKIGPENPYNTPVSAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
AGLKQKKSVTVLDVGDAYFSVPLDESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRAKNPELVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFYTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014