<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI|RTV|SQV NA
2 3TC+ABC+DDI+LPV+SQV 52

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I54V, L76V, I84V, L90M L10F, L33F W6C, I13V, M36MI, R41RK, L63P, I64V, I66V, H69R, I93L, C95F  
>410| codons 4-99
TLCQRPFVTVKIGGQLKEALLDTGADDTVFEEINLPGKWKPKIIGGIGGFVKVRQYDQIP
VEVCGRKAIGTVVVGPTPVNVIGRNLMTQLGFTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L74V, T215Y   K101KAET, Y181C, G190S   T39A, K122E, I135T, S162C, H221Y, V245Q  
>410| codons 38-247
CAELEKEGKISKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHP
AGLTKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSP
AIFQCSMTKILEPFRKQNPDIVICQYMDDLYVSSDLEIGQHRTKIEELRQHLLRWGFYTP
DKKYQKEPPFLWMGYELHPDKWTVQPIQLP

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014