<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method

Treatment History
Order Regimen Weeks
1 RTI NA
2 3TC+AZT+IDV 52
3 3TC+AZT+LPV 53

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, K14R, I15V, L19I, M36I, R41K, L63P, H69K, T74S, L89M, I93L  
>1183| codons 4-99
TLWQRPLVSIRVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYDQIP
IEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101KE   T39E, V60I, A98S, D121H, K122E, I135KR, K166R, K173A, Q174R, D177E, T200A, I202V, Q207E, R211K, V245Q  
>1183| codons 38-246
CEEMEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHP
SGLEKKKSVTVLDVGDAYFSVPLHEDFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSP
AIFQSSMTRILEPFRARNPEIVIYQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGFTTP
DKKHQKEPPFLWMGYELHPDKWTVQPIQL

References
Author Title Citation
Grossman, Z Comparable long-term efficacy of lopinavir/ritonavir and similar drug-resistance profiles in different HIV-1 subtypes. PLoS ONE, 2014